Ngo began his career as a multimedia editor for the Portland State University student newspaper, The Vanguard. He came to national attention when he was dismissed in 2017 after publishing a video to Twitter that the paper’s editor-in-chief said was out of context and violated journalist ethics. Ngo responded publicly in a piece in the National Review disputing that he made any misrepresentation. While reporting on a 2019 Proud Boys march in Portland, Ngo was attacked and injured by counter protesters. Ngo was hit with a milkshake and claimed that blows to his head caused him to suffer a brain injury. He blamed antifa activists for the assault. Ngo later testified on antifa and related First Amendment issues before a U.S. House subcommittee.